Rex and Van Kleiss clash, which ends in Rex using the water in the East River to weaken the soil sustaining Van Kleiss' abilities. She goes through a portal, saying that it was too late for him to stop Van Kleiss. If not rescued, the rods would destroy the surrounding areas. Six tells Rex he knows what to do. Rex then asks about the robot that he can build with his powers, but Six seems hesitant to answer. He is able to use his ear-link communicator to talk to Dr.
Now having reverted to his earlier, less-refined self, Rex has to help Six find his way back from heartless mercenary to the fatherly mentor he has come to know. The streets of most cities are destroyed by the and crowded with protesters. Rex goes on missions with his friends to all corners of the globe to deal with mutated creatures that threaten people. Meechum casually mentioning that he deserved it. His technical skill are useful whenever there is need for some hands on technical work.
Skwydd asks Rex what he is going to do now, proposing going to school. Rex is about to leave the school when he hears a roar; he rescues a small girl from a spider-like E. In the laboratory, an unconscious is going through the scanner. Providence then arrives on the scene, with Six, Holiday, , and Noah riding inside one of the tanks. Gabriel Rylander mentions that it was nice having the team back together again, and proposes that they start a new project together.
The plan goes awry when both of the girls cling to Rex, making Noah mad. Fortunately, he is rescued by Six and Holiday who were pretending to be Providence agents and reunites with Bobo and White Knight, who have their own defect team against New Providence's aggressive methods. Noah confesses to Rex that he works for White Knight. In the room with the six chambers, Van Kleiss walks in on the Consortium. Rex wants Circe to forget about the Pack and come with him to Providence, but she hesitantly refuses, saying it is not her life.
Surprisingly, he agrees to listen when Caesar mentions that he has some new ideas that they can work on. Holiday is unable to get Breach to cooperate; she tries firing probes at Breach, who instinctively opens portals to random spots around the world to protect herself. He quickly forgets this upon realizing that the enemy had managed to escape after the fight. Breach takes Quarry to take the blame, while Rex parts with his old friends. Several units fly in to arrest the Consortium, only to be stopped by the new powers granted to them by the. Although she is both trained as a medical doctor and research scientist. However the mutations are not always primal.
Rex faces Van Kleiss many times before throwing him into another machine. During this time-skip, Providence has adopted a new method of dealing with captured E. The episode starts with narrating recent events. During the fight Rex recovers several memories of his forgotten childhood past, including the time he spent with his family, and some encounters with Van Kleiss and Black Knight during the Nanite Project. Rex asks for a sign as he manages to get the ball into the hoop, and in that moment appears to make his decision.
He tries to open the doors so that they can stop the Consortium, but the system is locked down. He manages to cope with the Consortium's power and fights back. He then makes an even stronger build that can create unusually strong shields of super-energized nanites. Unfortunately, for Rex, it turns out that Circe's intention is to become a member of the villainous Pack by defeating a giant sea monster E. Six tries to stop him, but Caesar mentions that there is no need before revealing that only Rex can control the power in its pure state. Rex arrives at the base to finish what he started. However, he is met with opposition by the new Leader of the Pack, Biowulf, shortly after arriving along with forces led by the relentless Black Knight and her Black Pawns.
However, things head downhill when one prank ends up endangering the entire city. During the following meeting, the Consortium members complain that they were only given a fifth of the power they had been promised. After quarrels with each other, the two finally work together to stop a threat once created by Rex's brother, Caesar, the Alpha Nanite Michael Emerson. As a last resort, Rex must risk losing his memory to defeat the Consortium once and for all. Holiday come along with Rex when an anomaly is detected there. Now free of their captors, Caesar and Peter leave the laboratory to greet the others with Rylander jokingly mentioning that he would guard the equipment.
Providence has Breach in custody, but while Six and Bobo are detected in a desert somewhere, Rex cannot be located. Another ally that helps is the knowledgeable Doctor Holiday. Rex learns that it is all a plot to return Van Kleiss to life. Rex walks in and asks where were taken after being caught by Black Knight, but Six informs him that they are still looking for them. They are the 2nd-5th most dangerous men and women on Earth. Around this time, the scientists are shown having a meeting of their own back at the research facility. But upon discovering that she and his own brother seek to control E.
The battle results in a gigantic explosion, turning him back to normal and creating a giant crater around his body. Outside of the facility, Caesar discerns that Rex must have programmed all of the nanites in the new reactor to cure everyone in the world. Circe tries to get Rex to join her as one of the Pack, but he refuses. However, defeating them is not an easy task. Rex easily defeats Quarry and bargains with Breach to release Circe from her pocket dimension. Other times the threat can be more closer than anyone realizes.